Progression and Transformation in ET

Progression and transformation in ET

Do you know which factors should be considered when assessing the disease state of essential thrombocythemia (ET) patients at risk of transitioning to myelofibrosis (MF) or acute myeloid leukemia (AML)? Follow the talk by Professor Norio Komatsu to learn more about how ET can transition to MF or AML, the impact on patient survival, and the molecular events that are involved in this progression. 1,2

1.Tefferi A, Guglielmelli P, Larson DR, Finke C, Wassie EA, Pieri L, et al. Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis. Blood. 2014;124:2507-2513.2.Cerquozzi S and Tefferi A. Blast transformation and fibrotic progression in polycythemia vera and essential thrombocythemia: a literature review of incidence and risk factors. Blood Cancer Journal. 2015;5:e366.