MPN Guidelines and Their Use in Clinical Practice

Learn more about the guidelines for the treatment, diagnosis and management of myeloproliferative neoplasms (MPNs) from Professor Alessandro Vannucchi. Watch this video to learn more about the clinical trials which helped to form these guidelines, which focused on thrombosis and hemorrhage as endpoints, compliactions which are often associated with essential thrombocythemia.1, 2

1. Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391-405
2. Barbui T, Finazzi G, Alessandra C, Thiele J, Passamonti F, Rui E, et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization–essential thrombocythemia (IPSET-thrombosis). Blood. 2012;120(26):5128-33.